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06 January 2026

Coulter Partners Places Industry Veteran Mark Rothera as CEO of TreeFrog Therapeutics

Coulter Partners successfully led a search assignment for TreeFrog Therapeutics and is pleased to announce the placement of Mark Rothera as Chief Executive Officer (CEO).

TreeFrog Therapeutics is a French regenerative medicine biotech focused on providing mass access to cell therapies. By combining biophysics and engineering, they produce high-quality cells at unprecedented scale and cost-effectiveness through internal programs and strategic partnerships.

Mark Rothera has built a strong reputation, driving the successful scale up of multiple biotech companies, including most recently, Viracta, Silence Therapeutics and Orchard Therapeutics. Renowned for building strong leadership teams that advance novel medicines through development to regulatory approval and commercialization, Mark has focused much of his career on specialty diseases and novel modalities including gene therapy and RNAi therapies. In his earlier career, he held commercial lead roles in PTC Therapeutics, Aegerion, Shire, and GSK.

Elsy Boglioli, Chair of the Board of TreeFrog Therapeutics, commented: “On behalf of the Board, we are delighted to welcome Mark to TreeFrog. His 30+ years of biopharma leadership, including most recently, three biotech CEO roles in gene therapy and biologics, will be invaluable as we advance our Parkinson’s and liver programs, further strengthen our regenerative medicine platform and pursue strategic partnerships such as the one in place with Vertex for their Type 1 Diabetes pipeline.”

Elsy Boglioli added: “Finding a CEO who could bridge both European and US business cultures was a primary objective for us, and Coulter Partners was instrumental in navigating this complex requirement. Their global perspective and deep understanding of our unique mission allowed them to identify the perfect candidate who fits our specific cultural and strategic needs. We appreciated their diligent approach and expertise in delivering such a high-impact leadership placement as we enter our next phase of international growth.”

Nicolas Leray, Associate Partner at Coulter Partners added: “We were delighted to partner with TreeFrog during this pivotal leadership transition. This assignment is a testament to the excellence and collaborative approach of our teams on both sides of the Atlantic, which enables us to conduct seamless, simultaneous searches in the U.S. and Europe. We look forward to the impact Mark will undoubtedly have on TreeFrog’s next chapter.”

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Mark Rothera, CEO TreeFrog Therapeutics

Mark Rothera, CEO TreeFrog Therapeutics

Mark brings more than 35 years of experience in the biopharmaceutical industry, with a strong record of driving the successful scaling of multiple biotech companies in both private and public settings. TreeFrog marks his fourth CEO role. He most recently served as President and CEO of Viracta (Nasdaq: VIRX) and previously led Silence Therapeutics (Nasdaq: SLN), a clinical-stage RNAi platform company.

Mark’s first CEO role was with Orchard Therapeutics (Nasdaq: ORTX), where he oversaw its transformation from a UK-based startup into a leading transatlantic public gene therapy company. Prior to this, he served as Chief Commercial Officer of PTC Therapeutics (Nasdaq: PTCT) and held senior leadership positions at Aegerion Pharmaceuticals and Shire Human Genetic Therapies. Mark received an M.A. in Natural Sciences from Cambridge University and an M.B.A. from INSEAD.

About TreeFrog Therapeutics
TreeFrog Therapeutics is a French-based regenerative medicine biotech set to unlock access to cell therapies for millions of patients. TreeFrog is unique in its approach to cell therapy development, bringing together biophysicists, cell biologists and bioproduction engineers to address the challenges of the industry – producing and differentiating cells of quality at unprecedented scale, cost-effectively. To succeed in their mission of Cell Therapy for all, TreeFrog operates a business model that includes its own therapeutic programs and partnerships with leading biotech and industry players. Since 2021, the company has raised $82 million to advance a pipeline of stem cell-based therapies in regenerative medicine.

For further information, visit www.treefrog.fr
About Coulter Partners
We are executive search and leadership development specialists working to build a better future. As advisors and consultants to companies at the cutting edge of Health, Science, and Technology, we are united by our mission to build teams that change the world. Operating uniquely as one global team, we have honed our expertise, platform, and data for over two decades, working across three continents, and in 40 countries. Applying what we learn through our work with boards, leadership teams, and investors in the world’s most innovative companies, we bring together and develop the right people at the right time to propel them to achieve their worthwhile goals.

www.coulterpartners.com

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